Leiomyosarcoma: Unraveling the Mysteries of a Rare Soft Tissue Sarcoma

Dr. Gummallapu Akshaya, Dr Sheela S R

Abstract: Uterine leiomyosarcoma is a rare malignant tumor accounting for almost 2-5% of all uterine malignancies. The highest prevalence is seen in the pre and perimenopausal age group.Uterine Leiomyosarcoma often presents with abnormal vaginal bleeding (56%), palpable pelvic mass (54%), pelvic pain (22%). It is an aggressive tumor that is challenging to treat because of its high resistance to standard therapy, as evidenced by high rates of booth recurrence and progression. Most common sites for metastasisis to lungs (74%) followed by peritoneum (41%), bone (33%) and liver (27%) Due to its rarity, pathological diagnosis, surgical management, and systemic treatment are challenging. Treatment decision process in these tumors should be taken in a multidisciplinary tumor board.

Keywords: Uterine leiomyosarcoma, abnormal bleeding, metastatic cancer, treatment resistance, multidisciplinary management

How to Cite?: Dr. Gummallapu Akshaya, Dr Sheela S R, "Leiomyosarcoma: Unraveling the Mysteries of a Rare Soft Tissue Sarcoma", Volume 14 Issue 5, May 2025, International Journal of Science and Research (IJSR), Pages: 1145-1145, https://www.ijsr.net/getabstract.php?paperid=MR25517152533, DOI: https://dx.doi.org/10.21275/MR25517152533