Antifertility Effects of Aqueous Seed Extract of Foeniculum vulgare (Mill.) on Seminal Parameters of Male Albino Mice

Anand Kumar, S K Jasim Reja, Rajesh Kumar, Pushpalata Dubey

Abstract: This study examines the impact of aqueous seed extract of Foeniculum vulgare on several semen parameters in male albino mice, such as epididymal sperm count, seminal pH, sperm motility sperm mortality, and sperm abnormalities.24 male albino mice were included for this research. All mice were divided into two groups as control and treated group. The mice of treated group were administered daily with 0.1 ml (70 mg/kg bd. Wt.) of the aqueous seed extract of F. vulgare for a period of 45 days. They were sacrificed at intervals of 15, 30, and 45 days for analysis. Results on the test sample showed that the highly significant (p<0.001) decrease in sperm count, motility and seminal p after 45 days of exposure as compared to control group of mice. While highly significant increase in mortality and abnormality of spermatozoa were also observed after 45 days of exposure as compared to control group of mice. These findings indicate that the aqueous seed extract of Foeniculum vulgare has anti - fertility effects in male albino mice, as it adversely affects sperm count, motility, and viability, and increases sperm abnormalities.

Keywords: Anti - fertility, sperm count, sperm motility, sperm mortality, seminal pH, Foeniculum vulgare