Downloads: 1
India | Pathology | Volume 14 Issue 12, December 2025 | Pages: 483 - 487
A Prospective Study of Soft Tissue Tumors with Histo-Cytopathology Correlations in JLN Medical College Ajmer
Abstract: Introduction: Soft tissue tumors (STTs) originate from non-epithelial, extraskeletal structures, include tissues like adipose, fibrous connective tissue, skeletal muscle, blood vessels, peripheral nerves. Histopathology remains the gold standard; Fine Needle Aspiration Cytology (FNAC) plays a vital role for superficial masses. Objectives: To determine the distribution of age, sex, and site in STTs, to assess the relative incidence of benign, intermediate and malignant tumors. To evaluate the efficacy and diagnostic accuracy of FNAC in diagnosing STTs by comparing cytology results with histopathology findings. Methods The study was carried out on 100 patients with palpable soft tissue lumps over a two-year period from January 2023 to December 2024 in the Department of Pathology, JLN Medical College, Ajmer. Histopathological diagnosis was established on formalin-fixed, paraffin-embedded tissue sections using routine H&E stains. Special stains were used as needed. Observations: Of the 100 STTs, 96% were benign, 1% intermediate, 3% malignant. Benign tumors were common in the 30-40 years (21.88%), with a higher incidence in males (55) than females (45). FNAC showed a high diagnostic accuracy of 95%, sensitivity of 95.92%, PPV of 98.94%. Conclusion: Benign STTs predominate, commonly in extremities, adipocytic tumor (lipomas).
Keywords: Soft tissue tumors (STT), Fine Needle Aspiration Cytology (FNAC), Positive predictive value (ppv), Adipocytic tumors
How to Cite?: Dr. Prem Dhayal, Dr. Neena Kasliwal, Dr. Sonia Tanwar, Dr. Saumya Mathur, Dr. Sunil Kumar Sharan, Dr. Satish, "A Prospective Study of Soft Tissue Tumors with Histo-Cytopathology Correlations in JLN Medical College Ajmer", Volume 14 Issue 12, December 2025, International Journal of Science and Research (IJSR), Pages: 483-487, https://www.ijsr.net/getabstract.php?paperid=MR251206230439, DOI: https://dx.doi.org/10.21275/MR251206230439