Recurrent Peritonsillar Inflammation and Suspected Adenoid Regrowth in a Post-Tonsillectomy Adult With Sickle Cell Disease: A Case Report
Abstract: Background: Peritonsillar inflammation is uncommon in post-tonsillectomy adults, especially in those with multiple adenoidectomies. In patients with sickle cell disease (SCD), infection-related presentations may pose diagnostic challenges and have hematologic implications. Case Presentation: A 35-year-old woman with sickle cell disease presented with acute dysphagia, sore throat, and decreased oral intake. She had a history of childhood tonsillectomy and three previous adenoidectomies. Examination revealed right-sided peritonsillar bulging without visible pus. Imaging ruled out abscess. Flexible nasopharyngoscopy showed a nasopharyngeal mass suggestive of adenoid hypertrophy. She was treated empirically with IV antibiotics and corticosteroids and showed rapid improvement. A planned adenoid biopsy two months later revealed no residual adenoidal tissue. Conclusion: This case highlights the diagnostic complexity of peritonsillar inflammation in post-tonsillectomy adults and raises the possibility of adenoid regrowth or inflammatory hypertrophy. In patients with sickle cell disease, early intervention is essential to prevent systemic complications.
Keywords: Peritonsillar cellulitis, tonsillectomy, adenoid hypertrophy, sickle cell disease, pharyngitis, case report
How to Cite?: Maram Mohammed AlGhumlas, Ahmed Yahya AlAhmary, "Recurrent Peritonsillar Inflammation and Suspected Adenoid Regrowth in a Post-Tonsillectomy Adult With Sickle Cell Disease: A Case Report", Volume 14 Issue 10, October 2025, International Journal of Science and Research (IJSR), Pages: 1239-1240, https://www.ijsr.net/getabstract.php?paperid=MR251022135950, DOI: https://dx.doi.org/10.21275/MR251022135950