Evans Syndrome Secondary to Celiac Disease - A Case Report

Dr. R. Legha, Dr. Bhagya Prem

Abstract: This article presents a rare case of Evans syndrome, a challenging autoimmune disorder marked by concurrent autoimmune hemolytic anemia AIHA and immune thrombocytopenic purpura ITP, occurring secondary to celiac disease. A 36 - year - old female, adherent to a gluten - free diet due to her celiac condition, presented with symptoms of fatigue, weakness, and easy bruising. Clinical findings, including severe anemia and thrombocytopenia, along with positive serological tests, confirmed the diagnosis of Evans syndrome in the context of active celiac disease. Treatment involved corticosteroids, intravenous immunoglobulin IVIG, and Rituximab, leading to significant improvement. This case underscores the need for vigilant monitoring for autoimmune complications in patients with celiac disease, highlighting the potential interconnection between these conditions. The article calls for further investigation into the mechanisms linking Evans syndrome and celiac disease to improve patient outcomes

Keywords: Evans syndrome, celiac disease, autoimmune hemolytic anemia, immune thrombocytopenic purpura, autoimmune disorders