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Research Paper | Surgery | India | Volume 13 Issue 3, March 2024

Study to Evaluate the Effectiveness of Prophylactic Intravenous Heparin Injection in Preventing Flap Necrosis in Case of Ventral Hernias

Dr. J A Jayalal | Dr. Angeline Vincent | Dr K. Velmurugan | Dr. John Nickson | Dr. R. Amala

Abstract: Aim of the study: To study the effectiveness of prophylactic heparin intravenous injection to prevent flap necrosis for open mesh repair for all ventral hernias and incisional hernia. Objectives: To study the effectiveness of prophylactic intravenous heparin injection for all ventral hernias with procedure done open mesh repair in view of Flap necrosis Wound infection Wound dehiscence Seroma formation Mesh infection. Methodology: This study is a randomized control trial conducted in the department of general surgery Kanyakumari medical college from September 2023 to December 2023. A total of 60 patients were divided into two groups 30 patients in the interventional group treated with Intravenous heparin injection of 5000 IU iv Bd and 30 patients in the control group not receiving heparin injection were monitored for flap necrosis, wound infection, wound dehiscence, mesh infection. Results: A total number of 60 patients of which 38 [63.3percent] males and 22 [36.6 percent] females. The flap necrosis was significantly lower in the heparin treated patients and the duration of hospital stay was significantly shorter. Conclusion: Heparin injection associated with lesser incidence of flap necrosis wound infection wound dehiscence mesh infection and seroma formation compared to normal group.

Keywords: heparin injection, flap necrosis, wound infection, mesh repair, ventral hernias

Edition: Volume 13 Issue 3, March 2024,

Pages: 1829 - 1832