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Masters Thesis | Biochemistry | India | Volume 14 Issue 3, March 2025 | Popularity: 5.7 / 10
Study on Anticancer and Antidiabetic Role of Phyto Components in Different Extracts of Carica papaya and Ananas Cosmosus Samples
Rasu R, Tamilarasi V
Abstract: In today's world all the medicinal plants found on the earth have their unique medicinal usages and significances. Medicinal plants contain many bioactive compounds that can be used in the process of curing various human diseases. Papaya (Carica papaya) fruit is used as a traditional medicine in India for various ailments, including cancer. Likewise, pineapple (Ananas comosus) also used as a therapeutic agent. In this study phytochemicals components were analysed qualitatively and quantitatively using aqueous, ethanol and acetone extracts of Carica papaya and Ananas cosmosus samples. Further antioxidant study was carried out using the above solvent extract by DPPH and FRAP assay methods. Antibacterial study of the plant extracts was performed by disc diffusion method using Staphylococcus aureus and Klebsiella pneumoniae microorganisms. Anticancer activity of ethanolic extracts of Carica papaya and Ananas cosmosus samples was studied with the HCA-7 colon cancer cell lines and also examined the antidiabetic role of ethanolic extract of Carica papaya and Ananas cosmosus samples with the help of α-amylase and α-glucosidase activity. This present study confirms the presence of various phytocomponents in different proportion in the above plant extracts. These components play a major role in antioxidant and antibacterial activity. The ethanolic extracts of Carica papaya and Ananas cosmosus proved as an efficient therapeutic agent in the treatment of diabetes and cancer.
Keywords: Carica papaya, Ananas cosmosus, Extracts, Anticancer and Antidiabetic activity
Edition: Volume 14 Issue 3, March 2025
Pages: 238 - 248
DOI: https://www.doi.org/10.21275/MR24319194459
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