Clinical Significance of Platelet Indices (Mean Platelet Volume and Mean Platelet Volume-to-Lymphocyte Ratio) in Acute Coronary Syndrome: A Hospital-based Observational Study
Abstract: Background: The role of platelet indices, such as mean platelet volume (MPV) and MPV-tolymphocyte ratio (MPVLR), in diagnosing, and predicting the severity, and fatality in acute coronary syndrome (ACS) has not been extensively studied, particularly in Indian patients. Therefore, the study aimed to investigate the clinical significance of MPV and MPVLR in ACS. Materials and methods: This hospital-based observational study was conducted in tertiary care hospital in India. It included 110 ACS cases and an equal number of age- and sex-matched controls with chest pain of noncardiac origin. The primary objective was to compare MPV and MPVLR in ACS patients and controls. Secondary objectives included examining the associations between MPV, MPVLR, and different ACS types, as well as their correlation with the global registry of acute coronary events (GRACE) risk score and inhospital major adverse cardiovascular events (MACE). Results: Higher MPV and MPVLR were observed in ACS cases compared to controls [(11.1 ? 1.1 fL; 10.6 ? 1.3 fL, p
Keywords: MPV, MPVLR, ACS
How to Cite?: Dr. Nirmal Kumar NK, Dr. Umesh Verma, Dr. Yatish, Dr. MN Khan, "Clinical Significance of Platelet Indices (Mean Platelet Volume and Mean Platelet Volume-to-Lymphocyte Ratio) in Acute Coronary Syndrome: A Hospital-based Observational Study", Volume 13 Issue 12, December 2024, International Journal of Science and Research (IJSR), Pages: 961-965, https://www.ijsr.net/getabstract.php?paperid=MR241211205413, DOI: https://dx.doi.org/10.21275/MR241211205413