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Case Studies | Medicine | India | Volume 12 Issue 10, October 2023

Congenital Pain Insensitivity CIPA: A Comprehensive Case Report, Clinical Features, and Management Strategies in an 11-Year-Old Patient

Yamini Saraswathi Gurram ^[2] | Bhavana Jala Nerella ^[2]

Abstract: This is a case of congenital pain insensitivity. This case projects the main presenting complaints and clinical features and psychological condition of the patient. Congenital insensitivity to pain with anhidrosis (CIPA) is characterized by recurrent episodes of infections and unexplained fever, anhidrosis (inability to sweat), and absence of reaction to noxious stimuli, self-mutilating behavior, mental retardation and damages to oral structures. Methods of early diagnosis like genetic typing can help us understand the course of disease easier.

Keywords: Congenital Pain Insensitivity, Psychological Condition, Nociception, NGF-TRKA Signaling, Staphylococcus Aureus Infection, SCN9A and SCN11A Mutations

Edition: Volume 12 Issue 10, October 2023,

Pages: 84 - 85