International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Medicine | India | Volume 12 Issue 5, May 2023


Investigational Profile in Case of Subclinical Hypothyroidism and its Effect on Cardiovascular System

Dr. Neha Sharma [2] | Dr. R. V. Dosi | Dr. Hardik Rathwa | Dr. Satish Gurjar


Abstract: Introduction: Subclinical hypothyroidism (also known as compensated hypothyroidism or mild hypothyroidism) is a condition associated with a raised serum concentration of thyroid stimulating hormone (TSH) but a normal serum free thyroxine (FT4).1 Hypothyroidism leads to hypercholesterolemia due to increased level of LDL cholesterol. Aim: to determine ECG, ECHO and lipid profile changes in case of subclinical hypothyroidism. Methodology: This was a cross sectional observational study conducted on 40 patients at outpatient medicine department of SSG hospital, Vadodara. Results: In majority of patients, total cholesterol, HDL, LDL and VLDL were deranged. Triglycerides were within normal limits.24 (60.00%) patients had grade 1 LV diastolic dysfunction. No abnormality was detected in only 16 out of 40 patients (40.00%). Conclusion: There is association between Lipid Profile changes and 2D Echo changes. There is no major ECG change in patients with subclinical hypothyroidism. Subclinical Hypothyroidism can be considered as independent risk factor of cardiovascular system morbidity.


Keywords: Hypothyroidism, lipid pro?le, cardiac changes


Edition: Volume 12 Issue 5, May 2023,


Pages: 1968 - 1971


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