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Review Papers | Otorhinolaryngology | India | Volume 12 Issue 4, April 2023

A Clinicopathological Profile and management of Juvenile Nasopharyngeal Angiofibroma in a Tertiary Care Centre in Central India

Abhishek Katake | Dr. Rameshwar Pawar | Dr. Ashish Keche

Abstract: Aims and Objectives: To study the clinicopathological profile and to analyze the efficacy of pre operative embolisation and optimum surgical approach in management of angiofibroma. Material and Method: In present study, 23 patients diagnosed clinicallyand radiologically as a case of Juvenile Nasopharyngeal Angiofibroma. After clinical diagnosis, patients are subjected to Digitalsubtraction angiography followed by pre - op embolisation. Embolization was done using PVC particles and gelfoam and check angiography was done. Patients were treated surgically using Endoscopic or combined surgical approaches. Total intraoperative blood loss was calculatedafter surgery. Results: The mean age of the patients was found to be 17.4 years. The preoperative diagnosis was based on clinical findings and CT findings and the staging wasdone accordingly. The most common feeder was found to be internal maxillary artery in all the cases. Blood loss was minimal to moderate, only one patient had blood loss of around 2200 ml. Conclusion: Juvenile Nasopharyngeal Angiofibroma should be clinically diagnosed and managed by lesser invasive surgical approach, along with preoperative embolisation to minimise intraoperative bleeding. Drilling of the pterygoid wedge was done in all patients resulting in minimal recurrence.

Keywords: Juvenile Nasopharyngeal Angiofibroma (JNA), Embolization, Angiography, Pathogenesis

Edition: Volume 12 Issue 4, April 2023,

Pages: 948 - 951