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Review Papers | Molecular and Cellular Engineering | India | Volume 10 Issue 11, November 2021

Therapeutic Cloning in the Treatment of Parkinsons Disease using Mouse Models

Arijeet Dedhe | Aqdas Khan | Yash Kulkarni

Abstract: Therapeutic cloning can treat Parkinson's disease using mouse models. Using embryonic stem cells that are matched genetically, the infected tissue is replaced and the mouse is then treated with dopamine producing neurons, the absence of which causes Parkinson?s disease. These addition of artificial neurons are created by the mice's own cells in the lab. Stem cells can be grown into any cell. The dopaminergic neurons are developed form these stem cells. Dopamine is a hormone that is responsible for emotions in our body. Dopaminergic neurons are present in the mid brain and are responsible for the movement of muscles. The mouse's own cell is taken when creating dopaminergic neurons because it was proved to be more effective as different samples do not mimic the original cells. Cloning can prove to be one of the most essential step in treatment of many other diseases Diabetes, Cancer etc if all the particular cell lines are formed.

Keywords: Cloning, Embryonic SC, Mouse, Dopaminergic neurons

Edition: Volume 10 Issue 11, November 2021,

Pages: 1252 - 1256