Rare Case of Myasthenia Gravis with Thymoma in Middle Aged Male

Dr. Yeravelli Anusha, Dr. Erri Sandeep Reddy, Dr. Ranjith Kumar, Dr. Mounika

Abstract: Introduction: Myasthenia Gravis is a rare Auto Immune disorder with Auto Antibodies against the Acetylcholine receptors in the Skeletal Neuro - Muscular Junction. Case Details: We report a case of 44 years, Male Presented with Complaints of Diurnal variation of Limb weakness, Neck muscle weakness, Ptosis, Dysphagia with Positive Ice - Pack test. Serum Anti - AchR Antibodies were elevated and Repetitive Nerve Conduction Studies showed >10% Decremental Response and Evaluation by CECT showed presence of Thymoma. The Patient was Started on Pyridostigmine which showed Clinical benefit and the Patient was referred to Dept. of CTVS for Surgical Removal of Thymoma. Discussion: Myasthenia Gravis is a rare Auto Immune disorder characterized by motor Weakness with Diurnal Variation with Preserved Reflexes and absent Sensory symptoms. Diagnosis is done by measuring Sr. Anti AchR antibodies, Anti MuSK receptor antibodies and Repetitive Nerve Conduction Studies. Treatment includes Anti - Cholinesterases, Immuno- suppressive agents, Plasmapheresis. Conclusion: Generalized Myasthenia Gravis is a rare disorder that can be seen rarely in a middle aged male associated with Thymoma and is managed primarily with Anti Cholinesterases and Thymectomy has the significant role in Seropositive cases

Keywords: Myasthenia Gravis, auto immune disorder, limb weakness, thymoma, treatment

How to Cite?: Dr. Yeravelli Anusha, Dr. Erri Sandeep Reddy, Dr. Ranjith Kumar, Dr. Mounika, "Rare Case of Myasthenia Gravis with Thymoma in Middle Aged Male", Volume 13 Issue 5, May 2024, International Journal of Science and Research (IJSR), Pages: 1533-1535, https://www.ijsr.net/getabstract.php?paperid=ES24525141847, DOI: https://dx.doi.org/10.21275/ES24525141847