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Research Paper | Zoology | India | Volume 13 Issue 1, January 2024

A Study on the Effect of Organophosphorous Pesticide Profenfos on Hepato - Renal Organs of Labeo Rohita (Hamilton 1822)

Swapna Mishra | Rashmi Sao

Abstract: Organophosphorous pesticides are extensively used to control pests of different food (Vegetable, Fruits tea etc.) and non - food (Tobacco, cotton etc.) crops due to their rapid biodegradability and non - persistent nature but their broad spectrum of harmful effects extends far beyond the pests. Profenfos is an important widely used organophosphorous pesticide but its toxic effects on Labeo rohita are not well studied. The main objective of this paper is to carry out an empirical study to investigate the effect of different Sub - lethal concentrations of Profenfos on the hepato - renal organ of Labeo rohita. The pre - determinated LC50 value of Profenfos 0.1 mg/L was used for this study. The freshwater Teleost Labeo rohita (Hamilton) was exposed to a sub - lethal concentration of Profenfos (10%, 20% and 50% of LC50 Value) for 96 hours. The vital tissue liver and kidney were isolated and studied for the changes in the histology of these organs. The histopathological examination of the liver showed hepatic necrosis, haemorrhage vacuolation, glycogen vacuolation, and cellular swelling. The kidney showed different changes like degeneration of cell membrane, damage of renal tubules and hypertrophy of nuclei. The current study clearly revealed Profenfos as a potent hepato - renal toxic pesticide; therefore, the injudicious, indiscriminate, and extensive use of Profenfos should be prohibited or at least reduced and strictly monitored.

Keywords: Labeo rohita, Hepato - renal, Profenfos, Organophosphorous pesticide

Edition: Volume 13 Issue 1, January 2024,

Pages: 1801 - 1806