Estimation of Chloride, Sulfate, Sodium, Magnesium and Calcium in Sebacic Acid using Ion Chromatography with Suppressed Conductivity Detection

Dr. Chetan Chavan, Chanakya Thaker, Chetan Chaudhari, Dr. Subhash Udeshi

Abstract: A simple and sensitive ion chromatography (IC) method for the determination of Chloride, Sulfate, Sodium, Magnesium and Calcium from Sebacic acid has been developed and validated. Chloride and Sulfate was separated using high capacity anion exchange column and Sodium, Magnesium and Calcium was separated using cation exchange column. These ions had been analysed by suppressed conductivity detection. For both, anions and cations, linearity of the method has been tested in range of 0.1mg/L to 2.5mg/L, where correlation coefficient observed was >0.999. The limits of detection and quantification have also been established for both, anions and cations. This validated method showed good sensitivity, reproducibility, linerarity, specificity and robustness. Therefore, this method can be applicable for routine and regular analysis for anions and cations

Keywords: Sebacic acid, Chloride, Sulfate, Sodium, Magnesium, Calcium, Suppressed Conductivity detection, Ion Chromatography