Efficient and Green Protocol for the Synthesis of Hippuric Acid

Sachin S. Fawade, Revannath D. Dhokane, Dr. Sambhaji Pathare, Gitaram Waje

Abstract: The main aim of the green chemistry to addresses various concerns related to minimization of hazardous chemicals, use of safer green chemicals, catalyst and solvent. A One pot synthesis of Hippuric acid has been achieved starting from Glycine and Benzoyl chloride in the presence of Potassium carbonate as a Green base and Tartaric acid, Citric acid as a Green acid. The recent environmental concerns, we developed the most economical efficient and environmental friendly protocol for the synthesis of Hippuric acid in very good yield (>81 %).

Keywords: Hippuric acid, Potassium carbonate, Tartaric acid, Glycine, Citric acid