Hand Schuller Christian Disease: A Case Report with Oral Manifestation

Motaz Atia, Shaima Taj

Abstract: Langerhans cell histiocytosis is a group of diseases that result from langerhans cells or their precursors abnormal proliferation. The clinical manifestations are the result of infiltration and accumulation of the langerhans cells in tissues. We report a case of a three years boy with osteolytic lesions involving occipital, maxillary and mandibular bone. Additional periodontal tissues destruction was seen involving all four quadrants. Diagnosis was confirmed radiographically and histologically.

Keywords: Histiocytosis, Hand-schuller-christian disease, periodontal disease