International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 121 | Views: 208

Research Paper | Medical Surgical | India | Volume 8 Issue 9, September 2019


The Study of the Effect of Antenatal Corticosteroids on Requirement of Surfactant and Ventilator in Preterm Neonates

Dr. Smitha.K [2] | Dr. G. Nita [2]


Abstract: Background: Preterm birth is defined as live births occurring before 37 completed weeks of gestation.1 Preterm birth is a significant cause of perinatal morbidity and mortality. Nearly one half of all cases of congenital neurological disability, including cerebral palsy are a consequence of prematurity. Aim: a) To study the effect of antenatal corticosteroids on preterm neonates, b) Need for surfactant, c) Need for ventilator. Materials and methods: It’s a prospective study conducted in the Department of OBG, KIMS Hospital and Research Center, Bangalore, Karnataka.200 patients with preterm labour were selected for the study.136 patients had received antenatal corticosteroids.64 patients couldn’t receive antenatal corticosteroids as the patients had presented with active labour from September 2018 to August 2019. Group 1 – did not receive antenatal corticosteroids Group 2 – received antenatal corticosteroids Results: In group 1 requirement of surfactant and ventilator was 40.6 % and 71.9 % respectively whereas in group 2 requirement of surfactant and ventilator was 22.1 % and 41.2 % respectively. All these observations were statistically significant. Conclusion: Antenatal corticosteroid administration significantly reduces the requirement of surfactant and ventilator in preterm neonates. Every effort should be made to initiate antenatal corticosteroid therapy in women between 28 and 36weeks+6 days as soon as preterm delivery appears likely.


Keywords: antenatal corticosteroids, Preterm neonates, Surfactant


Edition: Volume 8 Issue 9, September 2019,


Pages: 509 - 511


How to Download this Article?

Type Your Valid Email Address below to Receive the Article PDF Link


Verification Code will appear in 2 Seconds ... Wait

Top