International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 164 | Views: 240

Research Paper | Biological Sciences | Indonesia | Volume 8 Issue 7, July 2019


Antioxidant and Anticancer Potential Test of Alikokop (Dischidia nythesiana) Leaf Methanol Extract

Ira Risye Manggribeth | Dingse Pandiangan [13] | Parluhutan Siahaan


Abstract: This study aimed to determine the antioxidant and anticancer activity of methanol extract of Alikokop leaves (Dischidia nythesiana). The extraction method used is maceration extraction using methanol solvent. The antioxidant activity test was carried out using the DPPH (1, 1-diphenyl-2-picrylhydrazyl) free radical deterrent method and the anticancer activity assay was carried out using the MTT (Microculture Tetrazolium) method using P-388 cancer cells. From this study, the antioxidant test results showed that the methanol extract of Alikokop leaves had antioxidant activity with moderate concentration, with IC50 of 67.136 & mu; g / mL, and the results of anticancer tests showed that methanol extract of Alikokop leaves had anticancer activity on leukemia cells P388 with concentration inhibition values medium, with IC50 of 24.88 & mu; g / mL. The methanol extract of Alikokop leaves has the potential as an antioxidant and anticancer leukemia.


Keywords: antioxidant, anticancer, alikokop, methanol exstract, Dischidia nythesiana


Edition: Volume 8 Issue 7, July 2019,


Pages: 1134 - 1140


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