Analysis of Outcomes of Proton Pump Inhibitors and H2 Receptors Antagonist

Manoj Kumar, Chandra Jyoti, Krishna Gopal

Abstract: In now days proton pump inhibitors are prescribing more and more by Indian physicians not only in pepticulcer, gastroesophageal reflux disease, gastritis but also along with non steroidal anti inflammatory drugs to overcome the side effects as gastric irritation and discomfort by non steroidal anti inflammatory drugs. There are many brands of PPI drugs available Proton pump inhibitors (PPI) are prescribing more and more by Indian physician and surgeons. Costly drugs can lead to economic burden which results in decreased compliance or even non-compliance. Non –compliance leads to incomplete treatment which tends to increase morbidity. Increase in the patient medication cost was found to associated with decreased adherence to prescription medication. Hence this study was done to assess the outcomes of proton pump inhibitors [PPI] drugs and H2 receptor antagonist. Our other objectives were to assess therapeutic appropriateness with standard guideline, ADR & Drug Interactions related to PPI & H2 receptor antagonist.

Keywords: PPI, Appropriateness Use, H2 Receptor Antagonist