International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Medical Microbiology | Nigeria | Volume 8 Issue 5, May 2019 | Rating: 7 / 10


Antiplasmodial and Toxicological Effects of Ethanolic Extracts of Moringaoleifera and Annonamuricata Leaves on Albino Rats

Okolie N.J.C. [2] | Akio Blessing


Abstract: Malaria is a disease caused by Plasmodia species. In a bid to address the health problems posed by malaria especially in tropical regions, plant based products are often being resorted to. This study was aimed at evaluating the anti-plasmodial and toxicological effects of Moringa oleifera and Annona muricata ethanolic leaf extracts in albino rats. In this study, the experimental animals were all (except for the normal control) inoculated with Plasmodium berghei infected erythrocytes and were treated with the plant extracts and reference drug (combisunate). The suppressive ability and Biochemical indices were carried out after five days of treatment. The results showed that there was reduction in the parasitemia level of the groups treated with Annona muricata relative to the untreated control which was significant at p


Keywords: Toxicological, antiplasmodial, Moringa oleifera, Annona muricata, Plasmodium berghei


Edition: Volume 8 Issue 5, May 2019,


Pages: 1772 - 1776


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