Copper (I)-N, N-Dimethyldipropylenetriamine Catalyzed Robust Homocoupling of Terminal Alkynes
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 119 | Views: 373 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Chemistry | India | Volume 7 Issue 10, October 2018 | Popularity: 6.3 / 10


     

Copper (I)-N, N-Dimethyldipropylenetriamine Catalyzed Robust Homocoupling of Terminal Alkynes

Pitchiah Tamilselvan, T. M. Dhiraj Karthik


Abstract: A robust catalytic system consisting of Cu (I) -salt and dimethyldipropylenetriamine for the synthesis of 1-4-disubstituted 1, 3-diynes have been developed. The new protocol involves homocoupling of terminal alkynes in the presence of CuI or CuCl and DMAPAPA as ligand in acetonitrile. A seires of terminal alkynes having diverse functional groups are converted to corresponding 1, 3-diynes via homocoupling under ambient conditions within an hour in excellent yields upto 98 %. The current protocol avoids stoichiometric amount of copper salt and high cost palladium salt, and harsher condition.


Keywords: homocoupling, copper catalysis, acetonitrile, terminal alkynes, 1, 3-diyne, DMAPAPA


Edition: Volume 7 Issue 10, October 2018


Pages: 1506 - 1510



Please Disable the Pop-Up Blocker of Web Browser

Verification Code will appear in 2 Seconds ... Wait



Text copied to Clipboard!
Pitchiah Tamilselvan, T. M. Dhiraj Karthik, "Copper (I)-N, N-Dimethyldipropylenetriamine Catalyzed Robust Homocoupling of Terminal Alkynes", International Journal of Science and Research (IJSR), Volume 7 Issue 10, October 2018, pp. 1506-1510, https://www.ijsr.net/getabstract.php?paperid=ART20192315, DOI: https://www.doi.org/10.21275/ART20192315

Top