Dynamic Investigation of ?-Hydroxy Amide Derivatives by 400 MHz 1H-NMR

Mehmet GUVEN, Mehmet Zafer KOYLU

Abstract: In this study, and relaxation times of some -hydroxy amide derivatives was measured at room temperature (25 0C) by 400 MHz 1H-NMR spectrometer. The motion of molecules was investigated by finding correlation time from the rate of. times of Ar-OH, Amide-NH and Alcohol-OH groups in -hydroxy amide 1 appears greater than the times of Ar-OH, Amide -NH and Alcohol groups in -hydroxy amide 2 and 3. This result shows that interactions as well as non-covalent intramolecular interactions in ligand 2 and 3 which carry more bulky groups. values of all molecules are found in ns range. This indicates that the motion is based on dipolar interactions.

Keywords: hydroxy amide, molecular dynamic, correlation time

How to Cite?: Mehmet GUVEN, Mehmet Zafer KOYLU, "Dynamic Investigation of ?-Hydroxy Amide Derivatives by 400 MHz 1H-NMR", Volume 7 Issue 10, October 2018, International Journal of Science and Research (IJSR), Pages: 1130-1133, https://www.ijsr.net/getabstract.php?paperid=ART20192166, DOI: https://dx.doi.org/10.21275/ART20192166