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Case Studies | Pathology | India | Volume 7 Issue 9, September 2018
Lymphoepithelioma Like Carcinoma of Urinary Bladder - A Rare Case Report
Dr. Neeru Singhal | Dr. Neelu Gupta [2]
Abstract: Lymphoepithelioma like carcinoma (LELCA) of urinary bladder (UB) is a rare variant of bladder cancer, characterized by malignant epithelial component densely infilterated by lymphoid cells and the malignant epithelial component characterized by indistinct cytoplasmic border, vesicular nuclei, prominent nucleoli arranged in syncytial growth pattern, which are cytokeratin marker positive on immunohistochemistry. These neoplasms must deserve attention and recognition as their definitive management has yet to be established and most of the study shows them chemotherapy responsive. We here represent a case study of 72 years old male presented with gross hematuria since one and half month. On CECT a mass was seen at lateral wall of UB. Tras urethral resection of UB was done and histopathalogical examination was carried out on this tissue showing LELCA along with few areas poorly differentiated urothelial carcinoma invading muscle. Immunohistochemistry show cytokeratin positivity.
Keywords: Lymphoepithelioma Like Carcinoma LELCA, Urinary Bladder UB, Epithelial component, Syncytial growth pattern
Edition: Volume 7 Issue 9, September 2018,
Pages: 1137 - 1138