Effect of Vitamin C and Dialium guineense Fruit Pulp Activity on HO-1, Insulin Secretion and Ace in Experimental Diabetes
Abstract: The study was targeted at evaluating the modulatory effect of aqueous fruit pulp of Dialium guineense on hemeoxygenase, insulin, angiotensin converting enzyme (ACE) and possible hypoglycemia in streptozotocin-induced diabetic rats. Twenty four male Wistar rats were randomly divided into four groups control, diabetic control (Dm), diabetic + 300 mg/kg body weight Dialium guineese (Dm+ DG) and diabetic + 500 mg/kg Vitamin C (Dm +Vit. C). Animals were made diabetic by injecting a single dose of 55 mg/kg streptozotocin intraperitoneally. Dialium and Vitamin C were administered orally for three weeks. Result showed significant (p
Keywords: Hemeoxygenase, angiotensin converting enzyme, , Dialium guineense, Diabetes, Vitamin C
How to Cite?: Etah Nkanu, Victoria Okon, Ujong Gabriel, Esther George, "Effect of Vitamin C and Dialium guineense Fruit Pulp Activity on HO-1, Insulin Secretion and Ace in Experimental Diabetes", Volume 7 Issue 9, September 2018, International Journal of Science and Research (IJSR), Pages: 355-361, https://www.ijsr.net/getabstract.php?paperid=ART20191120, DOI: https://dx.doi.org/10.21275/ART20191120