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Research Paper | Medical Microbiology | India | Volume 7 Issue 2, February 2018

Association of Severity of Chronic Obstructive Pulmonary Disease with Sputum Bacterial Isolation

Theresia Risa Davita | Abhishrut Pramod Jog

Abstract: Background Chronic Obstructive Pulmonary Disease is a frequent respiratory disease seen in chronic smokers. These patients suffer from episodes of exacerbations, commonly caused by bacterial infection. The study aimed at finding association of COPD severity with the bacteria isolated. Methods The study was conducted in Silchar Medical College, Assam in 114 patients. Sputum samples were sent for culture testing. Spirometry was performed to grade the severity. Results A significant association was found between increasing severity and greater isolation of Gram Negative bacteria (p-value < 0.05). Conclusion Gram Negative bacteria are a common cause of exacerbations in more severe cases of COPD.

Keywords: Chronic Obstructive Pulmonary Disease, Exacerbation, Sputum, Bacteria

Edition: Volume 7 Issue 2, February 2018,

Pages: 1146 - 1150