Prevalence of Renal Dysfunction in ART Naive HIV Positive Patients in Manipur, North East India

Wungreipam Kasar, Suresh Singh, N. Biplab Singh, Ksh. Birendra Singh

Abstract: Objective-HIV-related renal dysfunction is a known complication. Data regarding the same is lacking in Manipur, North Eastern India. Methods- A cross sectional study of 295 ART nave HIV positive cases was done to screen for the renal dysfunction using serum creatinine, spot proteinuria, 24 hour urine protein levels, creatinine clearance and CD4 cell counts. Results- 52/295 (17.62 %) showed proteinuria.43/52 (82.7 %) had 24 hour urine protein between 500-1000 mg/d while proteinuria >1g/d was seen in 9/52 (17.3 %) cases. Lower mean CD4 count were seen in proteinuria cases, as compared to those without renal involvement (221.7245.72 cells/mm3 versus 334.22324 cells/mm3, p value

Keywords: CD4 cell count, creatinine clearance, HIV, proteinuria, renal dysfunction