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Research Paper | Medicine Science | Sudan | Volume 6 Issue 9, September 2017
Assessment of Prostate Cancer Radiation Therapy Using PSA Level
Alaa M. Hassan | Mohammed Elfadil [3] | A. H. A. Bakry [5]
Abstract: This an analytical study aimed to assess radiation therapy for prostate cancer patients using PSA level in order to assess the treatment outcome in term of cellular reduction of PSA production, a total of 193 patients, age range (39-88) years old with mean (69.19.4) years prostate cancer treated with surgery (Partial and Total removal, partial dominant) and radical radiotherapy were included. Those patients referred to RIA lab at RICK, the study variables was included PSA level, age, TNM stage, weight, marital status, family history. The data collected using master data sheet after filling a questioner and analyzed using EXCELL software and statistical package for social science IBM-SPSS (21.0) in form of clustered column and curves. The result show overall 93 patients were reached references levels of PSA less than 1 and 1-4ng/ml which represented 48.1 percent in mean follow up for two months. The PSA-3 (After Radiation) was (17.1 24.1 ng/ml) for those with PSA-1 (Frist) were (87 48.6 ng/ml). Stage II (130) patient (67.36 %) & age group (64-70) years 61 patients (30.5 %) were dominant. This study also reveals that there is a significant difference between PSA levels before and after treatments at p=0.000 (CL=95 %), also the effect of surgery it seem to be more effective rather than radiotherapy in which mostly related to the delayed period between the planning procedure and treatment delivery this is mostly due to lack of machine availability at area of the study.
Keywords: Prostate cancer, Prostate-specific antigen, Radiation therapy and treatment outcome
Edition: Volume 6 Issue 9, September 2017,
Pages: 969 - 973