International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 115 | Views: 269

Research Paper | Hematology | Saudi Arabia | Volume 6 Issue 11, November 2017 | Popularity: 6.9 / 10


     

To Analyze the Impact of Prognostic Factors on Remission Induction in Acute Lymphoblastic Leukemia-A Tertiary Care Centre Study

Aiyesha Humaira, Syed Sami Ullah


Abstract: Objective To analyze the impact of prognostic factors on remission induction in acute lymphoblastic leukemia-A tertiary care centre study. Study Design Prospective and Cohort. Place and Duration of Study Aga Khan University Hospital, Karachi, data collected from March 2005 to February 2006. Materials and Methods 36 patients were evaluated to analyze the impact of prognostic factors on remission status after receiving 04 weeks of induction chemotherapy. Patients with acute lymphoblastic leukemia of all ages and gender were included and all other lymphoproliferative disorders, refractory and relapsed acute lymphoblastic leukemia were excluded in the study. A proforma was filled for each patient at the time of presentation. These patients were followed at the end of induction chemotherapy and remission status is assessed by bone marrow examination. Tests Performed on the Blood Samples. Chi-square test was applied to determine the significance. The P value 0.23). Although more cases were found in remission among ages between 1-20 years but the result was not statistically significant probably due to sample size. The remission is dependent of WBC count with a cutoff range 50x109/L (P0.23) and regarding immunophenotyping the remission is independent on immunophenotype seen on flow cytometry (P


Keywords: Prognostic factors, acute lymphoblastic leukemia, Remission induction


Edition: Volume 6 Issue 11, November 2017


Pages: 986 - 991



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!
Aiyesha Humaira, Syed Sami Ullah, "To Analyze the Impact of Prognostic Factors on Remission Induction in Acute Lymphoblastic Leukemia-A Tertiary Care Centre Study", International Journal of Science and Research (IJSR), Volume 6 Issue 11, November 2017, pp. 986-991, https://www.ijsr.net/getabstract.php?paperid=ART20177964, DOI: https://www.doi.org/10.21275/ART20177964



Similar Articles

Downloads: 107 | Weekly Hits: ⮙2 | Monthly Hits: ⮙2

Research Paper, Hematology, Iraq, Volume 8 Issue 8, August 2019

Pages: 1543 - 1553

The Value of Immunohistochemistry of P53 and Ki67 in Non-Hodgkin's Lymphoma

Dr. Harith Sami Ali, Dr. Israa Saadi Abbas, Dr. Ahmed Jassim Hammadee

Share this Article

Downloads: 122 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Hematology, India, Volume 4 Issue 9, September 2015

Pages: 207 - 209

To Evaluate a) the Effectiveness of Immature Reticulocyte Fraction (IRF) as Earliest Predictor of Bone Marrow Regeneration & b) To Test MRD as Strongest Predictor of Relapse in Pediatric Acute Leukemia's in Remission Induction Phase

Mirza Asif Baig

Share this Article



Top