A Correlation Study of Serum Uric Acid Level in Normal Pregnancy and Pregnancy Induced Hypertension

Mahendra R. Pakhale, Dr. Atul Padamawar

Abstract: Hypertension is one of the common complications met with in pregnancy and contributes significantly to the cause of maternal and perinatal morbidity and mortality. The study of uric acid in serum is an interesting problem especially in normal pregnancy and pregnancy induced hypertension (PIH). The study year 2016, the present study was carried out at Biochemistry and Gynaecology Department, shri Vasantrao Naik Government Medical College, Yavatmal on Total 80 subjects. Determination of uric acid was carried out by quantitative estimation on fully auto analyzer method by enzymatic uricase method. Results shows that Serum uric acid levels in both the time (predelivery and post-delivery) were statistically significant in Pregnancy induced hypertension than normal pregnancy. Many patients had predisposing factor to development of preeclampsia like primigravida. It is also evident that severity of proteinuria increases with diastolic blood pressure and Levels of serum uric acid did show a high positive correlation with the severity of Pregnancy induced hypertension in relation to hypertension and proteinuria 65 % of patients of PIH.

Keywords: Pregnancy, Hypertension, Uric Acid