Determination of Hydroquinone in Some Pharmaceutical and Cosmetic Preparations by Spectrophotometric Method

Hawaa S. Elferjani, Najw H. S. Ahmida, Aziza Ahmida

Abstract: In This study thirteen skin lighting creams are available in Libyan markets in Benghazi and Pharmaceutical Preparations were used to determine the content of hydroquinone by A rapid and simple UV spectrophotometric procedures. The labels on the packages noticeably did not show the content of hydroquinone. All samples were analysed by a UV spectrophotometer, Beers law was obeyed in the range of 10- 40 g/ml at 290nm using 0.05M H2SO4 as solvent with linear regression coefficient of 0.9994. The results showed the concentration of hydroquinone in all cosmetic samples ranged from 0.008 % to 0.210 %. The effect of time has been studied.

Keywords: hydroquinone, spectrophotometry, pharmaceutical and cosmetic preparations