Assessment of Thyroid Function in Major Thalassemia Patients above 12 Year of Age

Dr. Jyoti Prakash Yogi, Dr. Mukesh Soni, Dr. Prakash Keshwani

Abstract: Thyroid dysfunctions in patients with beta-thalassemia are the result of iron toxicity to thyroid cells. The present study was conducted in 160 subjects divided into two groups -Group A comprised of 80 diagnosed cases of -thalassemia major above 12 years of age receiving regular blood transfusions for more than last 3 years and at least 10 transfusions in a year. Group B comprised of age and sex matched 80 healthy individuals. We found that prevalence of hypothyroidism in patients with beta-thalassemia major was 20 % patients, which was significantly (p<0.0001) higher than the group B, in which prevalence of hypothyroidism was only 3.75 %.

Keywords: thalassemi amajor, Hypothyroidism

How to Cite?: Dr. Jyoti Prakash Yogi, Dr. Mukesh Soni, Dr. Prakash Keshwani, "Assessment of Thyroid Function in Major Thalassemia Patients above 12 Year of Age", Volume 6 Issue 7, July 2017, International Journal of Science and Research (IJSR), Pages: 67-69, https://www.ijsr.net/getabstract.php?paperid=ART20175120, DOI: https://dx.doi.org/10.21275/ART20175120