International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Microbiology | Volume 6 Issue 5, May 2017 | Pages: 2708 - 2711 | Nigeria


Effect of Moringa Oleifera Leaf Extract on Immunoglobulins of Albino Wistar Rats

Obiazi H. A. K., Okwu G. I., Akpe A. R., Omene O. B.

Abstract: The immune system is a host defense mechanism comprising many biological structures and processes within an organism that protects against disease. This study aims to determine the effect of aqueous extract of Moringa oleifera leaf on Immunoglobulin in Wistar rats. Twenty five (25) male rats were randomly divided into five (5) groups (A-E) of five (5) rats in each group. Group A served as control and were fed with conventional feed and distilled water only, while groups B, C, D and E served as test groups and received 20, 40, 60 and 80mg/kg body weight (bw) of the extract respectively. The administration was for 14 days. Thereafter groups B-E were inoculated with the test organisms and monitored for two weeks. At the end of administration, blood samples were collected by cardiac puncture and IgA, IgG and IgM levels were estimated by the immunoturbudrimetric method. Result obtained showed a significant (p

Keywords: Moringa oleifera, Immunoglobulin, Wistar Rats, immunomodulatory, test organisms

How to Cite?: Obiazi H. A. K., Okwu G. I., Akpe A. R., Omene O. B., "Effect of Moringa Oleifera Leaf Extract on Immunoglobulins of Albino Wistar Rats", Volume 6 Issue 5, May 2017, International Journal of Science and Research (IJSR), Pages: 2708-2711, https://www.ijsr.net/getabstract.php?paperid=ART20173574, DOI: https://dx.doi.org/10.21275/ART20173574

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