Influence of Irrigants and Intracanal Medicaments on the Vitality of Stem Cells from Apical Papilla - An Overview

Krasimir Hristov, Nataliya Gateva, Pavel Stanimirov

Abstract: Regenerative endodontics includes a therapy with new populations of mesenchymal stem cells, which are present in the apical papilla of teeth with incomplete root development, called stem cells from apical papilla. The preservation of these cells in the treatment of immature teeth may allow the continuation of root development to its final form and the closure of its apex. The choice of irrigants and intracanal medications in regenerative endodontics must be made taking into consideration their impact on the vitality of SCAP, in addition to their bactericidal/static effect.

Keywords: immature teeth, regenerative endodontics, stem cells from apical papilla