Synthesis of Silver Nanoparticles from Bauhinia acuminata Aqueous Leaf Extract and Molecular Docking Analysis of Various Cancer Receptors

Divya Sebastian, Albin T. Fleming

Abstract: To synthesize silver nanoparticle from Bauhinia acuminate aqueous leaf extract under various concentrations. The characterization Bauhinia acuminate silver nanoparticle using PSA shows the nanoparticle size of 78, 89 and 110 nm. The BaAgNPs were effective against E. coli and S. aureus was found to be 900 and 750 g using MIC assay. The molecular docking affinity of Caryophyllene oxide ligand binding to cellular receptors like 5DZL with -5.88 kcal/mol shows the effective nature of the aqueous leaf extract components. The BaAgNPs shows the effective antimicrobial inhibition against E. coli and S. aureus.

Keywords: BaAgNPs, PSA, MIC, Molecular Docking