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Research Paper | Dental Science | Volume 6 Issue 3, March 2017 | Pages: 139 - 142 | Indonesia
Effect of Collagen Membrane on Tumor Necrosis Factor-Alpha (TNF-?) Level in Wound Healing Process in Rats
Abstract: This study aimed to measure the TNF- level in rat blood serum during wound healing process using collagen membrane. Methods 24 male Wistar rats were divided into two groups treatment and control. A bone defect was created on the rats jaw using a 2 mm diamond bur. The defect was then covered with collagen membrane in the treatment group and without collagen membrane cover in control group. Results the average TNF- level in the treatment group was 209.7 pg/mL while in the control group the level was 487.3 pg/mL. There was a significant difference in the average TNF- level between the treatment and control groups (p= 0.03). Conclusions the use of collagen membrane can reduce the TNF- level in rats wound healing process.
Keywords: collagen membrane, TNF-, wound healing
How to Cite?: Agus Susanto, Susi Susanah, B. P. Priosoeryanto, Mieke Hemiawati Satari, "Effect of Collagen Membrane on Tumor Necrosis Factor-Alpha (TNF-?) Level in Wound Healing Process in Rats", Volume 6 Issue 3, March 2017, International Journal of Science and Research (IJSR), Pages: 139-142, https://www.ijsr.net/getabstract.php?paperid=ART20171313, DOI: https://dx.doi.org/10.21275/ART20171313