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Dissertation Chapters | Chemistry | Iraq | Volume 6 Issue 3, March 2017

Synthesis of New-2- Quinolone Sulfonphthalimide Derivatives

Luma S. Ahamed | Redha I. Al-Bayati | Mohammed R. Ahamad ^[2]

Abstract: Series of new different 2-quinolone derivatives linked to phthalimide sulphonyl moiety were performed via the following steps different prepared coumarins were converted to corresponding 2-quinolones by treating them with hydrazine hydrate then these 2-quinolones were treated with sulfonphthalimide derivative which was synthesized by two steps first step was performed by fusion of phthalic anhydride with aniline to produce 2-phenyl-isoindole-1, 3-dione, the later product treated with chloro sulfonic acid at cold condition to prouduce (1, 3-dioxo-1, 3-dihydro-isoindol-2-yl) which was treated with the different synthesized 2-quinolones to produce new 2- quinolone Sulfonphthalimide derivatives. The synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra and by measuring some of their physical properties

Keywords: 2-quinolones, coumarin, sulfonphthalimide, 2-Phenyl-isoindole-1, 3-dione

Edition: Volume 6 Issue 3, March 2017,

Pages: 301 - 310