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Research Paper | Oncology Science | India | Volume 5 Issue 12, December 2016

The Dosimetric Comparison of Doses Distribution of Co60 Based High Dose Rate Intracavitary Brachytherapy Delivered Under General Anaesthesia v/s Conscious Sedation in Cervical Cancer Patients

Poonam Chand Bana | Narendra Kumar Rathore

Abstract: This study compare prospectively the dosimetric distribution of doses delivered to point A, bladder and rectal reference point using CO60based ICRT under general anaesthesia v/s conscious sedation in cervical cancer patients. This study was conducted prospectively on 80 applications of ICRT in carcinoma cervix patients with stage IB2 to IIIB.40 applications in group AG (anaesthesia group) and 40 applications in group CS (conscious sedation group) those planned from October, 2015 to November, 2015. ICRT was done using Fletcher suit applicators (central tendem and two vaginal ovoids) and the machine named Eckert and Zeigler HDR remote after loading. In each application dose of 6 Gy was prescribed to point A and doses at bladder and rectal reference points (bladderref and rectalref) were noted and compared in both groups. Student t test was used to compare significance difference. Demography and clinical characteristics were comparable in both group. The mean dose to bladderref in group AG ranges from 17.7-69.2 % (1.07-4.14 Gy) and in Group CS from 15.54-74.24 % (0.93-4.45Gy). P value is 0.130 (insignificant). The mean dose to rectalref in group AG ranges from 32.5-77.73 % (1.95-4.78 Gy) and in Group CS it ranges from 21.07-79.16 % (1.26-4.75 Gy). P value is 0.126 (insignificant). So avoiding general anaesthesia doesnt result in inferior dosimetry in HDR brachytherapy in carcinoma cervix.

Keywords: oncology

Edition: Volume 5 Issue 12, December 2016,

Pages: 1524 - 1530