Haematological Parameters and Cellular Immune Response Associated with Administration of Polyvalent Schistosomamansoni Vaccine in Mice

Abdel-Hakeem | S.S. Abdel-Zaher | M. Abed G. H.

Abstract: Schistosomasis is one of the most tropical neglected diseases (NTDs), which have very complex antigenically different life stages. So that studying the effect of each antigen on cellular immune response is required. Three schistosomal antigens were used CAP, SEA and SWAP separately in vivo. Blood parameters and lymphocytes blastogenesis were evaluated. The most changes were reported in WBCs and differential cells with maximum immune response after 33 dpv in CAP and 47 dpv in SEA and SWAP. These changes reflected the defense and cellular immune response for each antigen.

Keywords: CAP, SEA, SWAP, schistosomasis, blastogenesis

Edition: Volume 5 Issue 12, December 2016,

Pages: 1548 - 1555

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Haematological Parameters and Cellular Immune Response Associated with Administration of Polyvalent Schistosomamansoni Vaccine in Mice

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