An Efficient and Simple Procedure for the Synthesis of 4-Substituted Coumarins by von-Pechmann Reaction using Mixture of FeCl3 and Tetrabutylammoniumbromide as Catalyst

Asitanga Ghosh

Abstract: von-Pechmann reaction is modified by using a cheap, easily available and a very effective Lewis acid catalyst - FeCl3. A series of 4-substituted coumarin derivatives have been prepared from a mixture of a phenol derivatives and ethyl acetoacetate using catalytic amount of FeCl3 in nitrobenzene in presence of phase transfer catalyst tetrabutylammoniumbromide

Keywords: von-Pechmann reaction, coumarin, phenol, ethyl acetoacetate and FeCl3 catalyst

How to Cite?: Asitanga Ghosh, "An Efficient and Simple Procedure for the Synthesis of 4-Substituted Coumarins by von-Pechmann Reaction using Mixture of FeCl3 and Tetrabutylammoniumbromide as Catalyst", Volume 5 Issue 12, December 2016, International Journal of Science and Research (IJSR), Pages: 974-976, https://www.ijsr.net/getabstract.php?paperid=ART20163573, DOI: https://dx.doi.org/10.21275/ART20163573