Follicular Fluid IL-6 Levels in Prediction of Successful Pregnancy Outcome in Women Undergoing IVF-ET Cycles - A Prospective Study
Abstract: Objective To investigate expediency of quantitative levels of interleukin-6 (IL-6) detected in follicular fluid (FF) of women underwent in-vitro fertilization-embryo transfer (IVF-ET) cycles. Design Prospective observational study. Method Study comprises evaluation of IVF/ICSI-ET cycles in relation to contribution of quantitative levels of IL-6. FF samples were collected on day of oocyte retrieval by pooling ovarian follicles of size 15mm for each woman (n=168). Enzyme-linked immunosorbent assay (ELISA) technique was applied for measuring quantitative level of IL-6. Demography, cycle characteristics, endometrial thickness, number of oocytes, fertilization rate, grading of embryos and IL-6 levels were compared between pregnant and non-pregnant groups of women. Student T-test, Mann Whitney U-test, Chi-squares test and logistic regression were applied as appropriate. Statistical significant level was calculated at P
Keywords: Infertile-women, Follicular-fluid, Interleukins, IVF-ET and Pregnancy-outcome
How to Cite?: Yogesh Kumar, Saumya Prasad, Syed Akhtar Husain, Ritu Goyal, Mohammad Aasif Khan, Shashi Sharma, Sudha Prasad, "Follicular Fluid IL-6 Levels in Prediction of Successful Pregnancy Outcome in Women Undergoing IVF-ET Cycles - A Prospective Study", Volume 5 Issue 10, October 2016, International Journal of Science and Research (IJSR), Pages: 1724-1732, https://www.ijsr.net/getabstract.php?paperid=ART20162410, DOI: https://dx.doi.org/10.21275/ART20162410