Downloads: 125 | Views: 157

Case Studies | Histopathology | India | Volume 5 Issue 10, October 2016

Darier's Disease: A Rare Disorder of Keratinisation. Case Report and Review of Literature

Sujata S Giriyan ^[9] | Archana B M

Abstract: Dariers disease or Keratosis Follicularis, is a rare autosomal dominant disorder which is characterised clinically by appearance of multiple pruritic, discrete, scaly papules affecting seborrhoeic areas coupled with palmar pits, nail changes and mucosal involvement. Histopathology of the lesions show suprabasal clefts with acantholytic and dyskeratotic cells.

Keywords: Autosomal dominant, palmar pits, suprabasal clefts, Dariers disease

Edition: Volume 5 Issue 10, October 2016,

Pages: 877 - 880