Formulation Development of Aqueous Topical Solutions and Gels of Poorly Water Soluble Drug Nimesulide, Using Novel Application of Mixed Solvency Concept and their Evaluations

Pawan Mulani, Rajesh Kumar Maheshwari

Abstract: Application of mixed solvency concept has been employed in the present research work to develop the topical solutions and gels of poorly water soluble drug, nimesulide.

Keywords: Solubility, nimesulide, topical solution, topical gel, mixed solvency concept, NSAID