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Research Paper | Physiology Science | Nigeria | Volume 7 Issue 3, March 2018
Effect of the hydromethanolic Extract of the Pulp of Garcinia kola Seed on Fertility Indices of Male Wistar Rats
Chibuike Obiandu [4] | Ologhaguo Adienbo [2]
Abstract: The incidence of infertility is on the increase, globally. However, the largest burden exist in Africa where it is still posing a major challenge in the reproductive health of couples. Male related factors also play a significant role in the incidence of infertility among couples. This study was done to investigate the effects of the pulp of Garcinia kola seed on fertility of male wistar rats. Male wistar rats were divided into three (3) groups of eight (8) rats each. Group one (1) which served as control received distilled water. Group two (2) and group three (3) were treated with 100mg/kg bw and 200mg/kg bw of the hydromethanolic (14) extract of the pulp of Garcinia kola seed respectively. This design was used in each case, for the sperm quality and hormonal studies which lasted for 58 and 60 days respectively. The results obtained showed that the extract caused significant increase in the serum levels of luteinizing hormone, testosterone, testicular weight as well as the percentage of actively motile cells and sperm count. This study proved that, the pulp of Garcinia kola possesses fertility enhancing effects in male wistar rats.
Keywords: Pulp, Garcinia kola, hydromethanolic, wistar rats, fertility
Edition: Volume 7 Issue 3, March 2018,
Pages: 803 - 807