Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Applied Chemistry | Morocco | Volume 6 Issue 8, August 2017 | Popularity: 6.3 / 10


     

Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides

Z. Tribak, M.K. Skalli, O. Senhaji, Y. Kandri Rodi


Abstract: A new series of dioxazoline of 5-Chloroisatin derivatives has been designed and synthesized involving 1, 3-dipolar cycloaddition reaction, preceded by a simple N-alkylation reaction in phase-transfer catalytic conditions The regioselectivity of the reactions was ascertained by 1H, 13C NMR spectroscopy of the synthesized compounds.


Keywords: 5-Chloroisatin, Dioxazoline, N-alkylation, 1, 3-Dipolar cycloaddition, 1H, 13C NMR spectroscopy


Edition: Volume 6 Issue 8, August 2017


Pages: 1145 - 1149



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Z. Tribak, M.K. Skalli, O. Senhaji, Y. Kandri Rodi, "Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides", International Journal of Science and Research (IJSR), Volume 6 Issue 8, August 2017, pp. 1145-1149, https://www.ijsr.net/getabstract.php?paperid=28071703, DOI: https://www.doi.org/10.21275/28071703