Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides

Z. Tribak, M.K. Skalli, O. Senhaji, Y. Kandri Rodi

Abstract: A new series of dioxazoline of 5-Chloroisatin derivatives has been designed and synthesized involving 1, 3-dipolar cycloaddition reaction, preceded by a simple N-alkylation reaction in phase-transfer catalytic conditions The regioselectivity of the reactions was ascertained by 1H, 13C NMR spectroscopy of the synthesized compounds.

Keywords: 5-Chloroisatin, Dioxazoline, N-alkylation, 1, 3-Dipolar cycloaddition, 1H, 13C NMR spectroscopy

How to Cite?: Z. Tribak, M.K. Skalli, O. Senhaji, Y. Kandri Rodi, "Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides", Volume 6 Issue 8, August 2017, International Journal of Science and Research (IJSR), Pages: 1145-1149, https://www.ijsr.net/getabstract.php?paperid=28071703, DOI: https://dx.doi.org/10.21275/28071703