Evaluation of Antioxidanat Activity of Melia azedarach On Depression Induced Rat Brain Tissue

A A. Leelavathi, V A Doss

Abstract: In the present study the antidepressant activity of Melia azedarach on depression induced rat brain tissues was evaluated. The aqueous extract showed significant increase in the levels of protein, cholesterol and significant decrease in LPO level when administered orally for 30 days to depression induced rats at a dose of 50 and 150 mg/kg body weight. phytochemical studies also revealed the presence of (flavanoids) in aqueous extract which may be responsible for exerting antidepressant activity. Hence it can be used as a drug for depression.

Keywords: Antioxidant, Melia azedarach, aqueous extract