International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 133 | Views: 229

Research Paper | Medicine Science | India | Volume 4 Issue 10, October 2015 | Rating: 6.2 / 10

Role of Lukol Syrup in Relieving the Symptoms Associated with Leucorrhoea: A Randomized, Double Blind Placebo Controlled Clinical Study

Dr. Cordelia Praveen MD DGO

Abstract: Vaginal discharge in the reproductive age group is the most common complaint encountered everyday both by gynecologists and general practitioners. The present study was conducted to evaluate the clinical efficacy and safety of Lukol Syrup in relieving symptoms associated with Leucorrhoea. Seventy women aged more than 30 years of age with symptoms of leucorrhoea enrolled in the study based on the selection critera. All the subjects were randomized to Lukol Syrup (Group A) and placebo group (Group B) using random number table. Subjects in the Lukol Syrup group received Lukol Syrup at a dose of 2 teaspoonful twice daily for 4 weeks and subjects in the placebo group received similar looking placebo at the same dose for 4 weeks. All subjects were followed at weeks 2 and 4 for the presence or absence of symptoms. The predefined primary efficacy endpoints were relief from the symptoms of leucorrhoea and safety of the formulation. The secondary outcome was to evaluate efficacy on the organism causing Leucorrhea and compliance to the study medication. This clinical study clearly shows that significant symptomatic relief was observed with Lukol Syrup in individuals with leucorrhoea. There were no adverse effects either observed or reported during the clinical study and compliance to the treatment was satisfactory. In terms of the microbiological examination, there was a trend towards improvement in individuals with Candida albicans and significant improvement in individuals with Trichomonas vaginalis. Therefore, it may be concluded that, Lukol Syrup is effective and safe in relieving the symptoms of leucorrhoea.

Keywords: Leucorrhoea, Lukol Syrup

Edition: Volume 4 Issue 10, October 2015,

Pages: 1764 - 1769

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