Yogendra Shrestha, Ramesh M Tambat, K. M. Veeranna Gowda
Abstract: Introduction: Empirical treatment is prescribed typically while waiting for the culture report. Appropriate empirical antibiotic therapy has been associated with decreased mortality in patients with many different types of infection, where inappropriate empirical antibiotic therapy (IEAT) requires a change in therapy and essentially receive delayed appropriate therapy. IEAT is an important factor contributing to the emergence of antibiotic-resistant bacteria, and it is well known, that a larger proportion of administered antibiotics is prescribed without proper indication. Methodology: Prescription containing antibiotic was selected, divided in different groups as per diagnosis, and was compared with the ICMR Treatment Guidelines for Antimicrobial Use in Common Syndromes 2019. Results: Ceftriaxone were commonly used as a empirical antibiotic therapy followed by piperacillin/tazobactam and amoxyclav. Our Study shows more variation on selection of empirical antibiotic in AFI, Infected pancreatic necrosis, and Sepsis cases between ICMR Treatment Guidelines for Antimicrobial Use in Common Syndromes 2019 and hospital practised. Conclusion: Initiation of antimicrobial stewardship program become more important considering increasing resistance of microbes towards antibiotic.
Keywords: Antibiotic resistant, Antimicrobial stewardship program, Empirical treatment