Downloads: 105
Research Paper | Civil Engineering | India | Volume 4 Issue 3, March 2015
Production of High Purity Solanesol from Impure Low Assay Tobacco Extract by Single Step Normal Phase Chromatography Method
Umesh Ingle | Arvind Lali
Abstract: Solanesol is an essential intermediate for the synthesis of valuable vitamins and anticancer drugs. In impure form, solanesol is available as low purity extracts of tobacco. This extract is a complex composition of waxes and various polar and non-polar constituents with solanesol. The work presented one step chromatography method for the generation of high purity (95 wt. %) solanesol from the crude 18 wt. % assay extract of tobacco. The mobile phase for the purification was selected on the basis of miscibility characteristics of impure extract with various solvents. Suitable adsorbent for purification was selected on the basis of elution selectivity and desorption ratio. Alumina was selected as an adsorbent for purification due to high binding capacity of 35.2 mg/ (mL of adsorbent), high elution selectivity and desorption ratio. Optimized process produces solanesol of 95 wt. % purity. The process provides single step scalable purification of solanesol with high purity and recovery.
Keywords: Solanesol, Normal phase chromatography, Alumina, Miscibility, Purification
Edition: Volume 4 Issue 3, March 2015,
Pages: 1460 - 1465
Similar Articles with Keyword 'Alumina'
Downloads: 113
M.Tech / M.E / PhD Thesis, Civil Engineering, India, Volume 5 Issue 4, April 2016
Pages: 955 - 959Impact of Clay Particles in Concrete
S. Selvamamundi | Dr. N. Mahendran | Dr. S. Anuradha
Downloads: 115
Research Paper, Civil Engineering, India, Volume 9 Issue 2, February 2020
Pages: 563 - 567Influence on Compressive Stregnth of Concrete on Addition of Micro Alumina Particles to Cement
Vishnu Chakravarty | Pukhraj Sahu