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Case Studies | Medical Surgical | India | Volume 4 Issue 2, February 2015
Ochronotic Spondyloarthropathy - A Case Report
Dr V.V. Narayana Rao | Dr. A. Ajay [2] | Dr. D. Srikanth Reddy
Abstract: Alkaptonuria is a disorder of tyrosine metabolism due to deficiency of homogentisic acid oxidase enzyme which results in accumulation of homogentisic acid [1]. Excess amounts of homogentisic acid gets oxidized and gets deposited in connective tissue leading to OCHRONOSIS. Characterstic features of ochronosis include blue black discoloration of connective tissues including sclera, cornea, articular cartilage, heart valves, auricular cartilage, tendons and ligaments. Alkaptonuric ochronosis particularly interesting because it can be detected based only on clinical signs and medical history. We herein present a patient with typical signs and symptoms such as darkening of urine, pigmentation of sclera, nails, ear cartilage and manifesting arthritis in the fourth decade
Keywords: Alkaptonuria, Arthritis, Homogentisic acid, Ochronosis, Spondyloarthropathy
Edition: Volume 4 Issue 2, February 2015,
Pages: 1022 - 1024
Similar Articles with Keyword 'Arthritis'
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Case Studies, Medical Surgical, Argentina, Volume 13 Issue 4, April 2024
Pages: 846 - 849Panophthalmitis Secondary to Septic Arthritis of the Knee - Case Report
D'Addino Jose | Paredes Julieta [2] | Grosso Cristina [2]
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Case Studies, Medical Surgical, India, Volume 10 Issue 12, December 2021
Pages: 829 - 830Idiopathic Multiple Rice Bodies in the Knee Joint without Rheumatoid Arthritis or Tuberculosis: A Case Report
Dr. Mazharuddin Ali Khan [3] | Dr. S Feroz Ahmed | Dr. D Kalyan Reddy